Nucleosides and Analogues
Medchemexpress LLC 2'-Deoxyguanosine monohydrate | 312693-72-4 | 99.7% | 5 G
2'-Deoxyguanosine monohydrate is a nucleoside composed of guanine and 2'-deoxyribose, and it is one of the basic structural units of DNA.
- The oxidation products may participate in DNA damage.
- May affect gene expression or induce cancer.
Medchemexpress LLC 2-amino-2'-deoxyadenosine | 4546-70-7 | MFCD00047240 | 99.6% | 266.26 g/mol | C10H14N6O3 | 1 ML
2-Amino-2'-deoxyadenosine is a deoxyribonucleoside analog used as a building block in oligonucleotide synthesis and nucleoside research. It is supplied as a ready-to-use solution in DMSO or as a solid, and is characterized by high purity for laboratory applications.
- Suitable for oligonucleotide synthesis and nucleoside modification studies.
- Available as a 10 mM solution in DMSO and in solid pack sizes for scale-up.
- High purity (99.62%) for research-grade applications.
- Molecular weight 266.26 g/mol; chemical formula C10H14N6O3.
Medchemexpress LLC 2'-Deoxyadenosine monohydrate | 16373-93-6 | 99.89% | 269.26 | 5 G
2'-Deoxyadenosine monohydrate is an adenine nucleoside with multiple biological roles, including inhibiting glucose-stimulated insulin release and islet cyclic AMP (cAMP) accumulation. It activates caspase-3 and promotes apoptosis, and inhibits S-adenosyl-L-homocysteine hydrolase (SAHH) activity. It has shown an anticancer effect on colon cancer and appears as a white to off-white solid.
- Inhibits glucose-stimulated insulin release
- Inhibits glucose-stimulated increases in islet cyclic AMP (cAMP) accumulation
- Activates caspase-3
- Promotes apoptosis
- Inhibits S-adenosyl-L-homocysteine hydrolase (SAHH) activity
- Demonstrated inhibitory effect on the growth of various cells, including anticancer effect on colon cancer
- Appears as a white to off-white solid
Medchemexpress LLC N6-Isopentenyladenosine | 7724-76-7 | 99.4% | 335.36 | 1 ML
N6-Isopentenyladenosine (Riboprine) is an RNA modification found in cytokinins, which are known to regulate plant growth and differentiation. It is also present in a subset of tRNAs, where it enhances the efficiency and accuracy of translation. This compound is an end product of the mevalonate pathway and functions as an autophagy inhibitor, demonstrating interesting anti-melanoma activity.
- RNA modification found in cytokinins
- Regulates plant growth/differentiation
- Improves efficiency and accuracy of translation in tRNAs
- End product of the mevalonate pathway
- Autophagy inhibitor
- Exhibits anti-melanoma activity
Medchemexpress LLC 2'-Deoxyadenosine 5'-triphosphate disodium | 74299-50-6 | 99.9% | 535.15 | 10 MG
2'-Deoxyadenosine 5'-triphosphate disodium is a nucleotide with important biological activities. It serves as a substrate for a variety of polymerases, including DNA polymerases and reverse transcriptases. This compound plays a key role in DNA synthesis and reverse transcription. It is also widely used in in vitro reactions in molecular biology research.
- Serves as a substrate for a variety of polymerases
- Plays a key role in DNA synthesis
- Plays a key role in reverse transcription
- Widely used in in vitro reactions in molecular biology research
Medchemexpress LLC 7-deaza-2'-deoxyadenosine | 60129-59-1 | >=97.0% | 250.25 g/mol | C11H14N4O3 | 50 MG
7-deaza-2'-deoxyadenosine is a deoxynucleoside analog used in biochemical research and nucleotide chemistry as a building block for oligonucleotide synthesis and related assays. It is typically supplied as a white solid for laboratory research and is intended for research use only.
- deoxynucleoside analog for nucleotide chemistry
- used as a building block in oligonucleotide synthesis
- supplied as a solid in milligram quantities for laboratory research
- intended for research use only, not for human or clinical use
Selleck Chemical LLC FAD disodium salt-E0705-5MG
Flavin Adenine Dinucleotide Disodium is a redox cofactor more specifically a prosthetic group of a protein involved in several important enzymatic reactions in metabolism
Apexbio Technology LLC Flavin adenine dinucleotide 146-14-5 50mg
Flavin adenine dinucleotide (CAS 146-14-5) is a redox-active cofactor integral to a wide range of metabolic processes Incorporated in numerous flavoproteins FAD facilitates electron transfer in critical enzymatic reactions predominantly within mitochondrial pathways Enzymes utilizing FAD include succinate dehydrogenase -ketoglutarate dehydrogenase folate/FAD-dependent tRNA methyltransferases and N-hydroxylating monooxygenases as well as proteins implicated in apoptosis While the majority of flavoproteins catalyze redox reactions a subset mediates non-redox processes such as lyase transferase isomerase and ligase activities FAD is widely employed in research to investigate enzyme mechanisms mitochondrial metabolism and cellular redox regulation
Medchemexpress LLC NAD P H-flavin reduc 20ug
NAD(P)H-flavin reductase is a recombinant His-tagged enzyme expressed in E. coli that catalyzes the reduction of soluble flavins using NADH or NADPH. Supplied as a lyophilized powder formulated in PBS with trehalose, it is intended for enzymatic assays and biochemical studies requiring a reliable flavin reductase reference reagent.
- Recombinant enzyme with N-terminal His tag.
- Catalyzes reduction of soluble flavins using NADH or NADPH.
- Supplied lyophilized from PBS with 6% trehalose.
- Purity greater than 90% by reducing SDS-PAGE.
- Low endotoxin level (<1 EU/μg).
- Stable when stored at -20°C; aliquot and freeze for long-term storage.
Medchemexpress LLC Flavin adenine dinucleotide disodium salt | 84366-81-4 | MFCD00005041 | 99.72% | 500 UG
Flavin adenine dinucleotide (FAD) disodium salt is a redox cofactor, specifically a prosthetic group of a protein, that participates in several important enzymatic reactions in metabolism. It is for research use only.
- Redox cofactor
- Prosthetic group of a protein
- Involved in several important enzymatic reactions in metabolism
Apexbio Technology LLC Flavin adenine dinucleotide disodium 84366-81-4 100mg
Flavin adenine dinucleotide disodium (CAS 84366-81-4) is an oxidoreductive cofactor widely utilized in biomedical research As a prosthetic group of flavoproteins it mediates reversible electron transfer reactions integral to cellular energy metabolism mitochondrial respiration and biological oxidation processes This compound is frequently employed to investigate the catalytic mechanisms of flavin-dependent enzymes such as dehydrogenases and oxidases Additionally it serves as a valuable tool in elucidating metabolic pathways and studying mitochondrial dysfunction associated with various pathological conditions
Medchemexpress LLC Flavin adenine dinucleotide | 146-14-5 | MFCD00041835 | 785.55 g/mol | C27H33N9O15P2 | 10 MG
Flavin adenine dinucleotide (FAD) analytical standard supplied as a 10 mg reference material for research and analytical applications. FAD is a redox cofactor involved in multiple enzymatic reactions and is suitable as a reference for qualitative and quantitative HPLC, GC, and MS methods.
- Analytical standard suitable for HPLC, GC, and MS assays.
- Used as a quantitative reference for method development and validation.
- CAS number 146-14-5; molecular formula C27H33N9O15P2.
- Provided as a 10 mg vial; additional sizes available on request.
- SDS and handling information available from the supplier.